Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | IDE | P14735 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HLCS | P50747 | 6/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341777 | 0.85 | TDP1 (0.60) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL3120163 | 0.83 | TDP1 (0.54) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL712974 | 0.82 | HLCS (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL6884034 | 0.82 | HLCS (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL6883588 | 0.81 | TDP1 (0.52) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL29750306 | 0.81 | TDP1 (0.60) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL2514439 | 0.81 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL2513356 | 0.81 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL8578177 | 0.81 | TDP1 (0.54) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL30482005 | 0.81 | TDP1 (0.60) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914607-B1 | PHOTOCLEAVABLE LINKER MOLECULES WITH DIARYLSULPHID BACKBONE FOR TRANSIENT BIOCONJUGATE SYNTHESIS | VENTANA MED SYST INC (US) | 2017-11-29 | — | — | EP | claimed |
| US-9790243-B2 | Photocleavable linker molecules with diarylsulphide backbone for transient bioconjugate synthesis | VENTANA MEDICAL SYSTEMS, INC. (US) | 2017-10-17 | — | — | US | claimed |
| US-20150284415-A1 | PHOTOCLEAVABLE LINKER MOLECULES WITH DIARYLSULPHID BACKBONE FOR TRANSIENT BIOCONJUGATE SYNTHESIS | VENTANA MED SYST INC (US) | 2015-10-08 | — | — | US | claimed |
| EP-2914607-A1 | PHOTOCLEAVABLE LINKER MOLECULES WITH DIARYLSULPHID BACKBONE FOR TRANSIENT BIOCONJUGATE SYNTHESIS | Ventana Medical Systems, Inc. (US) | 2015-09-09 | — | — | EP | claimed |
| WO-2014053397-A1 | PHOTOCLEAVABLE LINKER MOLECULES WITH DIARYLSULPHID BACKBONE FOR TRANSIENT BIOCONJUGATE SYNTHESIS | ROCHE DIAGNOSTICS GMBH (DE) | 2014-04-10 | — | — | WO | claimed |
| EP-2914607-B1 | PHOTOCLEAVABLE LINKER MOLECULES WITH DIARYLSULPHID BACKBONE FOR TRANSIENT BIOCONJUGATE SYNTHESIS | VENTANA MED SYST INC (US) | 2017-11-29 | — | — | EP | disclosed |
| US-9790243-B2 | Photocleavable linker molecules with diarylsulphide backbone for transient bioconjugate synthesis | VENTANA MEDICAL SYSTEMS, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-20150284415-A1 | PHOTOCLEAVABLE LINKER MOLECULES WITH DIARYLSULPHID BACKBONE FOR TRANSIENT BIOCONJUGATE SYNTHESIS | VENTANA MED SYST INC (US) | 2015-10-08 | — | — | US | disclosed |
| EP-2914607-A1 | PHOTOCLEAVABLE LINKER MOLECULES WITH DIARYLSULPHID BACKBONE FOR TRANSIENT BIOCONJUGATE SYNTHESIS | Ventana Medical Systems, Inc. (US) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014053397-A1 | PHOTOCLEAVABLE LINKER MOLECULES WITH DIARYLSULPHID BACKBONE FOR TRANSIENT BIOCONJUGATE SYNTHESIS | ROCHE DIAGNOSTICS GMBH (DE) | 2014-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284415-A1 | PHOTOCLEAVABLE LINKER MOLECULES WITH DIARYLSULPHID BACKBONE FOR TRANSIENT BIOCONJUGATE SYNTHESIS | DHFR, DTYMK, DNPEP | TDP1 1100/4885MEN1 2927/4885ABL1 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.