Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716131 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2NOTUMPOLBRECQLALDH1A1 | |
| SCHEMBL27745558 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2NOTUMPOLBRECQLALDH1A1 | |
| Hydrochloric Acid SCHEMBL1859868 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2NOTUMPOLBRECQLALDH1A1 | |
| SCHEMBL10440938 | 0.80 | NOTUM (0.59) | SMN1; SMN2NOTUMPOLBRECQLALDH1A1 | |
| SCHEMBL1859866 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2NOTUMPOLBRECQLALDH1A1 | |
| Benzene SCHEMBL7956618 | 0.79 | NOTUM (0.58) | SMN1; SMN2NOTUMPOLBRECQLALDH1A1 | |
| SCHEMBL27553596 | 0.79 | TSHR (0.56) | SMN1; SMN2NOTUMPOLBRECQLALDH1A1 | |
| SCHEMBL7954952 | 0.77 | SIGMAR1 (0.54) | SMN1; SMN2NOTUMPOLBRECQLALDH1A1 | |
| SCHEMBL28941360 | 0.77 | L3MBTL1 (0.64) | SMN1; SMN2NOTUMPOLBRECQLALDH1A1 | |
| SCHEMBL27483254 | 0.77 | NOTUM (0.51) | SMN1; SMN2NOTUMPOLBRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697739-B2 | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof | NOVARTIS AG (CH) | 2014-04-15 | — | — | US | disclosed |