Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4984050 | 0.90 | SIGMAR1 (0.51) | SIGMAR1SMN1; SMN2ALDH1A1NOTUMMAPT | |
| SCHEMBL6154763 | 0.87 | SIGMAR1 (0.57) | SIGMAR1SMN1; SMN2ALDH1A1GAANOTUM | |
| SCHEMBL1716131 | 0.85 | SMN1; SMN2 (0.56) | SIGMAR1SMN1; SMN2ALDH1A1GAANOTUM | |
| SCHEMBL27745558 | 0.79 | SMN1; SMN2 (0.56) | SIGMAR1SMN1; SMN2ALDH1A1GAANOTUM | |
| SCHEMBL6154765 | 0.78 | ALDH1A1 (0.43) | SIGMAR1SMN1; SMN2ALDH1A1GAANOTUM | |
| SCHEMBL1859866 | 0.77 | SMN1; SMN2 (0.54) | SIGMAR1SMN1; SMN2ALDH1A1GAANOTUM | |
| Hydrochloric Acid SCHEMBL1859868 | 0.77 | SMN1; SMN2 (0.54) | SIGMAR1SMN1; SMN2ALDH1A1GAANOTUM | |
| SCHEMBL10440938 | 0.77 | NOTUM (0.59) | SMN1; SMN2ALDH1A1GAANOTUMPOLB | |
| SCHEMBL15640486 | 0.77 | SMN1; SMN2 (0.50) | SIGMAR1SMN1; SMN2ALDH1A1GAANOTUM | |
| Benzene SCHEMBL7956618 | 0.76 | NOTUM (0.58) | SMN1; SMN2ALDH1A1NOTUMPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174924-B1 | Therapeutic guanidines | CAMBRIDGE NEUROSCIENCE, INC. | 2001-01-16 | — | — | US | disclosed |