Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15640929 | 1.00 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MC4RMAPK1 | |
| SCHEMBL181664 | 0.94 | MC4R (0.55) | KMT2AMEN1ALDH1A1MC4RCYP51A1 | |
| SCHEMBL181665 | 0.94 | MC4R (0.55) | KMT2AMEN1ALDH1A1MC4RCYP51A1 | |
| SCHEMBL15640731 | 0.92 | MC4R (0.43) | KMT2AMEN1ALDH1A1MC4RMAPK1 | |
| SCHEMBL15640730 | 0.92 | MC4R (0.43) | KMT2AMEN1ALDH1A1MC4RMAPK1 | |
| SCHEMBL181676 | 0.92 | CCKBR (0.44) | KMT2AMEN1ALDH1A1MC4RMAPK1 | |
| SCHEMBL181677 | 0.92 | CCKBR (0.44) | KMT2AMEN1ALDH1A1MC4RMAPK1 | |
| SCHEMBL182041 | 0.90 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MC4RMAPK1 | |
| SCHEMBL182040 | 0.90 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MC4RMAPK1 | |
| SCHEMBL181602 | 0.90 | MC4R (0.46) | KMT2AMEN1ALDH1A1MC4RCYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697877-B2 | Oxyindole derivatives with motilin receptor agonistic activity | RAQUALIA PHARMA INC. (JP) | 2014-04-15 | — | — | US | disclosed |
| US-20110312933-A1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | RAQUALIA PHARMA INC. (JP) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312933-A1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | GPR68, GPR88, GPR52 | KMT2A 3436/4885MEN1 1651/4885ALDH1A1 2947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.