SCHEMBL15655992

SCHEMBL15655992

C1=Cc2ccccc21.C=CC(=O)N(CCC[Si](OCC)(OCC)OCC)CCC[Si](OCC)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 4/20 0.34
P2RX1 P51575 2/20 0.34
P2RX3 P56373 2/20 0.34
ZDHHC20 Q5W0Z9 2/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
PTBP1 P26599 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
P2RX7 Q99572 1/20 0.33
GSTO1 P78417 1/20 0.32
RET P07949 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HPGD P15428 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15655347 0.87 ZDHHC20 (0.42) ZDHHC20ZDHHC2HPGD
SCHEMBL3889351 0.83 ZDHHC20 (0.42) ZDHHC20ZDHHC2HPGD
SCHEMBL2046249 0.74 ZDHHC20 (0.32) ZDHHC20ZDHHC2
SCHEMBL9764016 0.74 ZDHHC20 (0.41) ZDHHC20ZDHHC2
SCHEMBL7714456 0.72 ALDH1A1 (0.48) NPSR1
SCHEMBL4316811 0.72 ZDHHC20 (0.41) ZDHHC20ZDHHC2
SCHEMBL20982056 0.70 HDAC6 (0.47) NPSR1
SCHEMBL2565127 0.70 CA12 (0.32)
SCHEMBL17693473 0.69 ZDHHC20 (0.39) ZDHHC20ZDHHC2HPGD
SCHEMBL3400493 0.68 MEN1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9745479-B2 Adhesion promoter ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2017-08-29 US disclosed
EP-2727924-B1 ADHESION PROMOTER ROHM & HAAS ELECT MAT (US) 2016-08-03 EP disclosed
US-9273215-B2 Adhesion promoter ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2016-03-01 US disclosed
US-20160040021-A1 ADHESION PROMOTER U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-02-11 US disclosed
EP-2727924-A1 Adhesion promoter Rohm and Haas Electronic Materials LLC (US) 2014-05-07 EP disclosed
US-20140120244-A1 ADHESION PROMOTER ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2014-05-01 US disclosed