SCHEMBL2046249

SCHEMBL2046249

C=CC(=O)N(C)CCC[Si](OCC)(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 2/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15655347 0.85 ZDHHC20 (0.42) ZDHHC20ZDHHC2
SCHEMBL907561 0.83 ZDHHC20 (0.30) ZDHHC20ZDHHC2
SCHEMBL3889351 0.81 ZDHHC20 (0.42) ZDHHC20ZDHHC2
SCHEMBL9398065 0.81
SCHEMBL19712273 0.80 ALDH1A1 (0.31)
SCHEMBL3212658 0.80 CHRM1 (0.31)
SCHEMBL3207871 0.80 EPHX2 (0.30)
SCHEMBL3341522 0.80 BCHE (0.31)
SCHEMBL9396079 0.78
SCHEMBL10863727 0.78 ALOX15 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346786-B1 USE OF SILICON-CONTAINING POLYMERS FOR IMPROVED FLOCCULATION OF SOLIDS IN PROCESSES FOR THE PRODUCTION OF ALUMINA FROM BAUXITE CYTEC TECH CORP (US) 2015-09-16 EP disclosed
EP-1381651-B1 POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM DOW CORNING TORAY CO LTD (JP) 2011-06-29 EP disclosed
WO-2010044986-A1 USE OF SILICON-CONTAINING POLYMERS FOR IMPROVED FLOCCULATION OF SOLIDS IN PROCESSES FOR THE PRODUCTION OF ALUMINA FROM BAUXITE CYTEC TECHNOLOGY CORP. (US) 2010-04-22 WO disclosed
EP-1858982-B1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT DOW CORNING (US) 2008-08-27 EP disclosed
US-20080182833-A1 Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient DOW CORNING CORPORATION 2008-07-31 US disclosed
CN-101142279-A Silicone emulsion, method of preparing same, and cosmetic ingredient DOW CORNING (US) 2008-03-12 CN disclosed
EP-1858982-A1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT Dow Corning Corporation (US) 2007-11-28 EP disclosed
US-7300648-B2 Polyorganosiloxane emulsion composition and a cosmetic material made therefrom DOWECORNING TORAY SILICONE, CO., LTD. (JP) 2007-11-27 US disclosed
WO-2006102010-A1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT DOW CORNING CORPORATION (US) 2006-09-28 WO disclosed
US-20040147647-A1 Polyorganosiloxane micro-emulsion composition and raw material for cosmetics DOW CORNING TORAY SILICONE CO., LTD. (JP) 2004-07-29 US disclosed
US-20040138373-A1 Polyorganosiloxane emulsion composition and a cosmetic material made therefrom DOW TORAY CO., LTD. (JP) 2004-07-15 US disclosed
CN-1505663-A Polyorganosiloxane emulsion composition and a cosmetic material made therefrom ������������ʽ���� 2004-06-16 CN disclosed
EP-1381651-A1 POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM Dow Corning Toray Silicone Co.,Ltd. Patent Department (JP) 2004-01-21 EP disclosed
WO-2002088253-A1 POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182833-A1 Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient SQLE, CUTA, SMOX ZDHHC20 2230/4885ZDHHC2 3308/4885CASP1 1696/4885
US-20040147647-A1 Polyorganosiloxane micro-emulsion composition and raw material for cosmetics UNG, PHOSPHO1, TPMT ZDHHC20 1574/4885ZDHHC2 2148/4885CASP1 3328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.