SCHEMBL15664493

SCHEMBL15664493

Nc1ccccc1CCCCSS(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.36
FDPS P14324 1/20 0.35
TTR P02766 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
GAA P10253 1/20 0.32
BID P55957 1/20 0.32
BCL2L1 Q07817 1/20 0.32
MCL1 Q07820 1/20 0.32
BAK1 Q16611 1/20 0.32
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CYP2C9 P11712 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15664372 0.98 MGLL (0.39) MGLLFDPSTTRSIGMAR1GAA
SCHEMBL15665008 0.98 MGLL (0.39) MGLLFDPSTTRSIGMAR1GAA
SCHEMBL15664485 0.95 FDPS (0.36) MGLLFDPSTTRSIGMAR1GAA
SCHEMBL15664457 0.88 FDPS (0.38) FDPSTTRSIGMAR1GAACA2
SCHEMBL27700317 0.78 MGLL (0.46) MGLLFDPSTTRSIGMAR1GAA
SCHEMBL15665043 0.78 FDPS (0.40) FDPSTTRGAACA2CA12
SCHEMBL23159850 0.76 ALOX15 (0.47) FDPSSIGMAR1GAAALOX15TSHR
SCHEMBL11285123 0.76 MGLL (0.40) MGLLFDPSTTRSIGMAR1GAA
SCHEMBL23159817 0.74 SIGMAR1 (0.46) MGLLFDPSSIGMAR1ALOX15TSHR
SCHEMBL15665038 0.73 MAOB (0.48) MGLLCA2CA12CA1CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103804723-B Tyre element and preparation method thereof 东洋橡胶工业株式会社 2016-09-07 CN disclosed
US-8946325-B2 Tire member and method for manufacturing the same TOYO TIRE & RUBBER CO., LTD. (JP) 2015-02-03 US disclosed
CN-103804723-A Tire member and method for manufacturing the same TOYO TIRE & RUBBER CO 2014-05-21 CN disclosed
CN-103804725-A Tire member and method for manufacturing the same TOYO TIRE & RUBBER CO 2014-05-21 CN disclosed
US-20140128525-A1 TIRE MEMBER AND METHOD FOR MANUFACTURING THE SAME TOYO TIRE & RUBBER CO., LTD. (JP) 2014-05-08 US disclosed
US-20140128498-A1 TIRE MEMBER AND METHOD FOR MANUFACTURING THE SAME TOYO TIRE & RUBBER CO., LTD. (JP) 2014-05-08 US disclosed