SCHEMBL15670703

SCHEMBL15670703

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nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.59
LMNA P02545 1/20 0.55
GBA1 P04062 1/20 0.55
IGF2R P11717 4/20 0.47
ADSS2 P30520 1/20 0.44
AMDHD2 Q9Y303 1/20 0.43
UMPS P11172 5/20 0.42
DNPH1 O43598 1/20 0.42
HPRT1 P00492 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50310 1.00 FBP1 (0.59) FBP1LMNAGBA1IGF2RADSS2
SCHEMBL25778394 1.00 FBP1 (0.59) FBP1LMNAGBA1IGF2RADSS2
SCHEMBL2028658 1.00 FBP1 (0.59) FBP1LMNAGBA1IGF2RADSS2
SCHEMBL29223798 0.76 FBP1 (0.55) FBP1IGF2RADSS2AMDHD2UMPS
SCHEMBL30189347 0.75 FBP1 (1.00) FBP1IGF2RAMDHD2UMPSDNPH1
SCHEMBL20154711 0.75 FBP1 (1.00) FBP1IGF2RAMDHD2UMPSDNPH1
SCHEMBL7129042 0.74 LMNA (0.56) LMNAGBA1IGF2R
SCHEMBL13997127 0.74 LMNA (0.56) LMNAGBA1IGF2R
Gluconolactone SCHEMBL11053856 0.72 LMNA (0.76) FBP1LMNAGBA1
Gluconolactone SCHEMBL24637666 0.71 LMNA (1.00) LMNAGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912043-A1 NEW ANTIBACTERIAL COMPOUNDS AND BIOLOGICAL APPLICATIONS THEREOF LABORATOIRE BIODIM (FR) 2015-09-02 EP disclosed
WO-2014067904-A1 NEW ANTIBACTERIAL COMPOUNDS AND BIOLOGICAL APPLICATIONS THEREOF LABORATOIRE BIODIM (FR) 2014-05-08 WO disclosed