Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | IGF2R | P11717 | 4/20 | 0.47 |
| ▸ | ADSS2 | P30520 | 1/20 | 0.44 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.43 |
| ▸ | UMPS | P11172 | 5/20 | 0.42 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50310 | 1.00 | FBP1 (0.59) | FBP1LMNAGBA1IGF2RADSS2 | |
| SCHEMBL25778394 | 1.00 | FBP1 (0.59) | FBP1LMNAGBA1IGF2RADSS2 | |
| SCHEMBL15670703 | 1.00 | FBP1 (0.59) | FBP1LMNAGBA1IGF2RADSS2 | |
| SCHEMBL29223798 | 0.76 | FBP1 (0.55) | FBP1IGF2RADSS2AMDHD2UMPS | |
| SCHEMBL30189347 | 0.75 | FBP1 (1.00) | FBP1IGF2RAMDHD2UMPSDNPH1 | |
| SCHEMBL20154711 | 0.75 | FBP1 (1.00) | FBP1IGF2RAMDHD2UMPSDNPH1 | |
| SCHEMBL7129042 | 0.74 | LMNA (0.56) | LMNAGBA1IGF2R | |
| SCHEMBL13997127 | 0.74 | LMNA (0.56) | LMNAGBA1IGF2R | |
| Gluconolactone SCHEMBL11053856 | 0.72 | LMNA (0.76) | FBP1LMNAGBA1 | |
| Gluconolactone SCHEMBL24637666 | 0.71 | LMNA (1.00) | LMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353375-B2 | Compositions and methods of PGL for the increased production of isoprene | DANISCO US INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-20150104853-A1 | COMPOSITIONS AND METHODS OF PGL FOR THE INCREASED PRODUCTION OF ISOPRENE | DANISCO US INC. | 2015-04-16 | — | — | US | disclosed |
| EP-2857518-A2 | Compositions and methods of PGL for the increased production of isoprene | Danisco US Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| EP-2516654-B1 | COMPOSITIONS AND METHODS FOR THE INCREASED PRODUCTION OF ISOPRENE WITH 6-PHOSPHOGLUCONOLACTONASE (PGL) | DANISCO US INC (US) | 2015-01-21 | — | — | EP | disclosed |
| US-8889387-B2 | Use of recombinant PGL for increased production of isoprene | DANISCO US INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-20130295633-A1 | COMPOSITIONS AND METHODS OF PGL FOR THE INCREASED PRODUCTION OF ISOPRENE | DANISCO US INC. | 2013-11-07 | — | — | US | disclosed |
| US-8455236-B2 | Compositions and methods of PGL for the increased production of isoprene | DANISCO US INC. (US) | 2013-06-04 | — | — | US | disclosed |
| EP-2553107-A2 | PENTOSE PHOSPHATE PATHWAY UPREGULATION TO INCREASE PRODUCTION OF NON-NATIVE PRODUCTS OF INTEREST IN TRANSGENIC MICROORGANISMS | E.I. Du Pont De Nemours And Company (US) | 2013-02-06 | — | — | EP | disclosed |
| EP-2516654-A2 | COMPOSITIONS AND METHODS OF PGL FOR THE INCREASED PRODUCTION OF ISOPRENE | Danisco US Inc. (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011123407-A2 | PENTOSE PHOSPHATE PATHWAY UPREGULATION TO INCREASE PRODUCTION OF NON-NATIVE PRODUCTS OF INTEREST IN TRANSGENIC MICROORGANISMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20110244512-A1 | PENTOSE PHOSPHATE PATHWAY UPREGULATION TO INCREASE PRODUCTION OF NON-NATIVE PRODUCTS OF INTEREST IN TRANSGENIC MICROORGANISMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-06 | — | — | US | disclosed |
| WO-2011079314-A2 | COMPOSITIONS AND METHODS OF PGL FOR THE INCREASED PRODUCTION OF ISOPRENE | DANISCO US INC. (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110159557-A1 | COMPOSITIONS AND METHODS OF PGL FOR THE INCREASED PRODUCTION OF ISOPRENE | DANISCO US INC. (US) | 2011-06-30 | — | — | US | disclosed |