Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851144 | 1.00 | LMNA (0.56) | LMNAALDH1A1MTORTP53HTT | |
| SCHEMBL1520633 | 0.82 | MAPT (0.52) | LMNAALDH1A1MTORTP53HTT | |
| SCHEMBL29136140 | 0.79 | ATIC (0.62) | SMN1; SMN2ADORA1 | |
| SCHEMBL19876125 | 0.79 | ATIC (0.62) | SMN1; SMN2ADORA1 | |
| SCHEMBL188235 | 0.79 | ATIC (0.62) | SMN1; SMN2ADORA1 | |
| SCHEMBL9697804 | 0.78 | MAPT (0.49) | LMNAALDH1A1MTORTP53HTT | |
| SCHEMBL17113147 | 0.78 | MAPT (0.49) | LMNAALDH1A1MTORTP53HTT | |
| SCHEMBL4879356 | 0.78 | ADORA3 (0.48) | LMNAHBBPMP22MAPTSMN1; SMN2 | |
| SCHEMBL13065920 | 0.77 | SMN1; SMN2 (0.56) | LMNAALDH1A1MTORTP53HTT | |
| SCHEMBL27715435 | 0.77 | TP53 (0.66) | LMNAALDH1A1MTORTP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014067038-A1 | TARGET POINT, PREPARATION AND METHOD FOR TREATING HUMAN ADSL DEFICIENCY | 广州百赫医疗信息科技有限公司 (CN) | 2014-05-08 | — | — | WO | disclosed |