Trehalose

Trehalose

SCHEMBL156806

OC[C@@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
PTPN1 P18031 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.55
GAA P10253 1/20 0.53
TYR P14679 1/20 0.53
MAPT P10636 1/20 0.53
LGALS8 O00214 2/20 0.51
LGALS3 P17931 2/20 0.51
LGALS4 P56470 1/20 0.51
LGALS9 O00182 1/20 0.50
LGALS1 P09382 1/20 0.50
GJA1 P17302 1/20 0.50
GJB2 P29033 1/20 0.50
CYP2C9 P11712 1/20 0.50
TSHR P16473 1/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trehalose SCHEMBL14472517 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL13465987 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
SCHEMBL5316713 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL25304700 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL17072366 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL23029503 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
SCHEMBL5399869 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL17072437 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL670041 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA
Trehalose SCHEMBL15497371 1.00 MEN1 (0.57) MEN1KMT2APTPN1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 688 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023067675-A1 ORAL COMPOSITION CONTAINING TREHALOSE 日本たばこ産業株式会社 2023-04-27 WO claimed
US-20220154137-A1 CELL CULTURE MEDIUM AGENCY FOR SCIENCE, TECHNOLOGY AND REASEARCH (SG) 2022-05-19 US claimed
US-20210355454-A1 SYSTEMS AND METHODS FOR PRODUCING GENE THERAPY FORMULATIONS VOYAGER THERAPEUTICS, INC. 2021-11-18 US claimed
US-11160766-B2 Peritoneal therapeutic fluid OPTERION HEALTH AG (CH) 2021-11-02 US claimed
EP-3324951-B1 PERITONEAL THERAPEUTIC FLUID OPTERION HEALTH AG (CH) 2021-05-26 EP claimed
EP-3420072-A1 CELL CULTURE MEDIUM Agency for Science, Technology and Research (SG) 2019-01-02 EP claimed
EP-3250051-B1 A NATURAL SWEETENING COMPOSITION OF LUO HAN GUO AND APPLE MONTERO GIDA SANAYI VE TICARET AS (TR) 2018-11-07 EP claimed
WO-2017146646-A1 CELL CULTURE MEDIUM AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-08-31 WO claimed
EP-3205336-A1 TREATMENT OF TISSUE ADHESION Mallinckrodt Pharma IP Trading D.A.C. (IE) 2017-08-16 EP claimed
US-20170127675-A1 COMPOSITIONS AND METHODS FOR CONTROLLING INSECT POPULATIONS OLFACTOR LABORATORIES, INC. (US) 2017-05-11 US claimed
EP-1652527-A1 ACCELERATOR FOR MINERAL ABSORPTION AND USE THEREOF KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2006-05-03 EP claimed
EP-1192947-B1 Pharmaceutical composition comprising trehalose for ophthalmic use HAYASHIBARA BIOCHEM LAB (JP) 2006-04-19 EP claimed
EP-1600143-A1 SKIN PREPARATION FOR EXTERNAL USE CHARACTERIZED BY CONTAINING SUGAR DERIVATIVE OF a,a-TREHALOSE Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2005-11-30 EP claimed
US-20050215493-A1 Calcium-containing tissue strengthening agents and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2005-09-29 US claimed
EP-1568283-A1 METHOD OF INHIBITING ACRYLAMIDE FORMATION AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2005-08-31 EP claimed
EP-1514540-A1 CALCIUM-CONTAINING TISSUE STRENGTHENING AGENTS AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2005-03-16 EP claimed
US-20050054585-A1 Agent controlling the production of osteoclast formation regulator and method of screening substance capable of controlling the production of osteoclast formation regulator KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKY 2005-03-10 US claimed
US-20050009017-A1 Alpha-isomaltosyltransferase, process for producing the same and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2005-01-13 US claimed
EP-1447085-A1 AGENT CONTROLLING THE PRODUCTION OF OSTEOCLAST FORMATION REGULATOR AND METHOD OF SCREENING SUBSTANCE CAPABLE OF CONTROLLING THE PRODUCTION OF OSTEOCLAST FORMATION REGULATOR Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2004-08-18 EP claimed
EP-1284286-A1 ALPHA-ISOMALTOSYLTRANSFERASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2003-02-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11160766-B2 Peritoneal therapeutic fluid FABP6, ALB, FABP2 MEN1 4429/4885KMT2A 2838/4885PTPN1 2090/4885
US-20050215493-A1 Calcium-containing tissue strengthening agents and use thereof ATP2A3, ATP2A1, ATP2A2 MEN1 2080/4885KMT2A 4558/4885PTPN1 4715/4885
US-20050009017-A1 Alpha-isomaltosyltransferase, process for producing the same and use thereof UGGT1, B4GALT1, GALE MEN1 2624/4885KMT2A 2370/4885PTPN1 1692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.