Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.46 |
| ▸ | KDM5C | P41229 | 3/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.46 |
| ▸ | KDM4B | O94953 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1568234 | 0.91 | NR3C2 (0.51) | KDM5BKDM5CKDM4AKDM4BNR3C2 | |
| SCHEMBL1569193 | 0.83 | BRD4 (0.55) | KDM5BKDM5CKDM4AKDM4BNR3C2 | |
| SCHEMBL16115747 | 0.81 | KDM4E (0.49) | KDM5BKDM5CKDM4AKDM4BLMNA | |
| SCHEMBL3634347 | 0.80 | KDM4E (0.59) | KDM5BKDM5CKDM4AKDM4BLMNA | |
| SCHEMBL3630367 | 0.79 | KDM4E (0.58) | KDM5BKDM5CKDM4BKCNH2LMNA | |
| SCHEMBL27542831 | 0.78 | KDM4C (0.63) | KDM5BKDM5CKDM4AKDM4BNR3C2 | |
| SCHEMBL5147899 | 0.78 | TSHR (0.51) | KDM5BKDM5CKDM4AKDM4BLMNA | |
| SCHEMBL29038570 | 0.78 | LMNA (0.56) | KDM5BKDM5COPRK1KCNH2LMNA | |
| SCHEMBL29038561 | 0.78 | LMNA (0.56) | KDM5BKDM5COPRK1KCNH2LMNA | |
| Hydrochloric Acid SCHEMBL30523486 | 0.77 | KDM4C (0.61) | KDM5BKDM5CKDM4AKDM4BNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307379-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2011-04-13 | — | — | EP | disclosed |