Benzimidazole

Benzimidazole

SCHEMBL156872

COC(N)=O.c1ccc2[nH]cnc2c1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ QPCT Q16769 4/20 0.47
▸ KDM4E B2RXH2 4/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ RAB9A P51151 2/20 0.45
▸ HPGD P15428 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ PARP1 P09874 1/20 0.45
▸ MMP12 P39900 1/20 0.44
▸ MAPT P10636 2/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ HDAC6 Q9UBN7 1/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ POLB P06746 4/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ CTNNB1 P35222 1/20 0.42
▸ WNT3A P56704 1/20 0.42
▸ NAMPT P43490 1/20 0.42
▸ CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzimidazole SCHEMBL28192710 0.93 QPCT (0.42) QPCTKDM4EALDH1A1SMN1; SMN2RAB9A
Benzimidazole SCHEMBL9028632 0.88 SMN1; SMN2 (0.49) QPCTKDM4EALDH1A1SMN1; SMN2RAB9A
Benzimidazole SCHEMBL4371075 0.88 KDM4E (0.51) QPCTKDM4EALDH1A1SMN1; SMN2RAB9A
Benzimidazole SCHEMBL5070094 0.88 KDM4E (0.51) QPCTKDM4EALDH1A1SMN1; SMN2RAB9A
Benzimidazole SCHEMBL158526 0.86 SMN1; SMN2 (0.54) QPCTKDM4EALDH1A1SMN1; SMN2RAB9A
Benzimidazole SCHEMBL27531290 0.86 KDM4E (0.42) QPCTKDM4EALDH1A1SMN1; SMN2RAB9A
Benzimidazole SCHEMBL11810774 0.85 KDM4E (0.46) QPCTKDM4EALDH1A1SMN1; SMN2RAB9A
Benzimidazole SCHEMBL28190538 0.84 ALDH1A1 (0.41) QPCTKDM4EALDH1A1SMN1; SMN2RAB9A
Benzimidazole SCHEMBL28188814 0.84 KMT2A (0.47) KDM4EALDH1A1SMN1; SMN2RAB9AHPGD
Benzimidazole SCHEMBL10531809 0.84 KDM4E (0.49) QPCTKDM4EALDH1A1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 999 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4618758-A1 MIXTURES OF SUCCINATE DEHYDROGENASE INHIBITORS AND PICOLINAMIDES FMC Corporation (US) 2025-09-24 — — EP claimed
US-20250098677-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-03-27 — — US claimed
US-20250089717-A1 FUNGICIDAL HALOMETHYL KETONES, HYDRATES AND ENOL ETHERS AND THEIR MIXTURES FMC CORP (US) 2025-03-20 — — US claimed
CN-116987433-B Polyurethane coating with high elongation and low attenuation, preparation method and application 立邦涂料(中国)有限公司 2024-12-10 — — CN claimed
CN-118973399-A Fungicidal combinations, mixtures and combinations and use thereof 安道麦马克西姆有限公司 2024-11-15 — — CN claimed
EP-3726994-B1 BCA CONTROL OF STB DANSTAR FERMENT AG (CH) 2024-09-11 — — EP claimed
CN-118325397-B Organic antibacterial mildew-proof liquid 上海膜益信息科技有限公司 2024-09-10 — — CN claimed
CN-118516020-A Preparation method of novel ion long-acting antiviral water paint 广东砂鸵涂料科技有限公司 2024-08-20 — — CN claimed
CN-118217722-A Filter medium and use thereof 东丽纤维研究所(中国)有限公司 2024-06-21 — — CN claimed
WO-2024107910-A1 MIXTURES OF SUCCINATE DEHYDROGENASE INHIBITORS AND PICOLINAMIDES FMC CORPORATION (US) 2024-05-23 — — WO claimed
WO-2009055514-A2 FUNGICIDAL MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-04-30 — — WO claimed
US-20080207448-A1 Containing fungicide and fumgi enhancing compound such as isoflavone; plant growth regulators VAMTECH, L.L.C. (US) 2008-08-28 — — US claimed
WO-2008103422-A2 COATED SEEDS AND METHODS OF MAKING COATED SEEDS VAMTECH L.L.C. (US) 2008-08-28 — — WO claimed
CN-1116480-C Exothermal infrared paper and its production process LIU LEI (CN) 2003-07-30 — — CN claimed
CN-1107449-C Liquid preservative for fruit and vegetable storage and preparation method thereof STATE AGRICULTURAL PRODUCT PRE (CN) 2003-05-07 — — CN claimed
CN-1334012-A Liquid preservative for fruit and vegetable storage and preparation method thereof STATE AGRICULTURAL PRODUCT PRE (CN) 2002-02-06 — — CN claimed
CN-1295152-A Exothermal infrared paper and its production process LIU LEI (CN) 2001-05-16 — — CN claimed
US-5800673-A HYDROPHILIC RESIN COATING ON TUBES SHOWA ALUMINUM CORPORATION (JP) 1998-09-01 — — US claimed
US-5527711-A Method and reagents for binding chemical analytes to a substrate surface, and related analytical devices and diagnostic techniques HEWLETT PACKARD COMPANY (US) 1996-06-18 — — US claimed
US-5470431-A Tubes with core plates, fins and headers, drainage canals and resin coverings SHOWA ALUMINUM CORP. (JP) 1995-11-28 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250098677-A1 FUNGICIDAL COMPOSITIONS CYP51A1, CYP4X1, CYP1B1 QPCT 2932/4885KDM4E 1660/4885ALDH1A1 477/4885
US-20250089717-A1 FUNGICIDAL HALOMETHYL KETONES, HYDRATES AND ENOL ETHERS AND THEIR MIXTURES HCN2, CYP8B1, TUBA3C QPCT 4363/4885KDM4E 1940/4885ALDH1A1 1492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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