Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12490981 | 0.81 | NOD2 (0.55) | ALDH1A1KDM4EL3MBTL1F10GRK6 | |
| SCHEMBL5005300 | 0.80 | CA12 (0.53) | CA1CA2CA12CA7CA9 | |
| SCHEMBL701977 | 0.79 | KDM4E (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30995157 | 0.76 | NOD2 (0.53) | ALDH1A1KDM4EL3MBTL1F10GRK6 | |
| SCHEMBL30995142 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EL3MBTL1F10GRK6 | |
| SCHEMBL27633995 | 0.75 | NOTUM (0.39) | ALDH1A1KDM4EL3MBTL1ATMRAB9A | |
| SCHEMBL5584948 | 0.75 | F10 (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30995245 | 0.74 | LMNA (0.37) | ALDH1A1KDM4EL3MBTL1GRK6RAB9A | |
| SCHEMBL914734 | 0.73 | CA12 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL31505722 | 0.73 | NOD2 (0.50) | ALDH1A1KDM4EL3MBTL1F10GRK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307422-A1 | NOVEL SPIROCHROMANONE CARBOXYLIC ACIDS | Banyu Pharmaceutical Co., Ltd. (JP) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010002010-A1 | NOVEL SPIROCHROMANONE CARBOXYLIC ACIDS | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-01-07 | — | — | WO | disclosed |