Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995245 | 0.88 | LMNA (0.37) | ALDH1A1SMN1; SMN2LMNAELANEGRK6 | |
| SCHEMBL30995182 | 0.85 | WDR5 (0.42) | ALDH1A1SMN1; SMN2LMNAELANEKDM4E | |
| SCHEMBL30995240 | 0.85 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNAELANEKDM4E | |
| SCHEMBL30995181 | 0.85 | WDR5 (0.42) | ALDH1A1SMN1; SMN2LMNAELANEKDM4E | |
| SCHEMBL30995218 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAELANEKDM4EL3MBTL1 | |
| SCHEMBL30995195 | 0.82 | NOTUM (0.42) | ALDH1A1LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL30995116 | 0.79 | NOD2 (0.42) | ALDH1A1SMN1; SMN2LMNAELANEKDM4E | |
| SCHEMBL20822415 | 0.79 | LMNA (0.46) | ALDH1A1SMN1; SMN2LMNAELANEGRK6 | |
| SCHEMBL30076067 | 0.79 | LMNA (0.46) | ALDH1A1SMN1; SMN2LMNAELANEGRK6 | |
| SCHEMBL7478527 | 0.76 | GRK6 (0.41) | ALDH1A1SMN1; SMN2LMNAGRK6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |