Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15722714 | 0.91 | TACR1 (0.35) | ALDH1A1TACR1 | |
| SCHEMBL9130782 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1TACR1CYP1A1 | |
| SCHEMBL14485345 | 0.71 | SIGMAR1 (0.39) | ALDH1A1TSHRMAPK1KMT2A | |
| SCHEMBL14556102 | 0.68 | ADRB2 (0.36) | ALDH1A1TSHRMAPK1KMT2AAOC3 | |
| SCHEMBL11139589 | 0.68 | MIF (0.38) | ALDH1A1TSHRMAPK1AOC3 | |
| SCHEMBL28161507 | 0.66 | ALDH1A1 (0.48) | ALDH1A1TACR1CYP1A1CYP1B1POLB | |
| SCHEMBL6318730 | 0.66 | ALDH1A1 (0.46) | ALDH1A1POLBAOC3 | |
| SCHEMBL6318735 | 0.66 | ALDH1A1 (0.46) | ALDH1A1POLBAOC3 | |
| SCHEMBL18782394 | 0.65 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPK1CYP1A1CYP1B1 | |
| SCHEMBL11152331 | 0.65 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160052863-A1 | PROCESS FOR PRODUCING AN AMINOPROPYNE OR ENAMINONE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-02-25 | — | — | US | disclosed |
| US-9193668-B2 | Process for producing an aminopropyne or enaminone | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-11-24 | — | — | US | disclosed |
| US-9193668-B2 | Process for producing an aminopropyne or enaminone | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-11-24 | — | — | US | disclosed |
| US-20140142304-A1 | PROCESS FOR PRODUCING AN AMINOPROPYNE OR ENAMINONE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-05-22 | — | — | US | disclosed |
| US-20140142304-A1 | PROCESS FOR PRODUCING AN AMINOPROPYNE OR ENAMINONE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142304-A1 | PROCESS FOR PRODUCING AN AMINOPROPYNE OR ENAMINONE | AADAT, AAAS, AADAC | ALDH1A1 1020/4885TSHR 934/4885MAPK1 695/4885 |
| US-20160052863-A1 | PROCESS FOR PRODUCING AN AMINOPROPYNE OR ENAMINONE | AADAT, AAAS, AADAC | ALDH1A1 1020/4885TSHR 934/4885MAPK1 695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.