SCHEMBL15712349

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15712344	0.88	P2RX3 (0.46)	DHODHKMT2AMEN1KDM4EALDH1A1
	SCHEMBL15712614	0.83	MPO (0.46)	DHODHMPOKMT2AMEN1LMNA
	SCHEMBL15712628	0.83	NR1I2 (0.59)	DHODHNR1I2
	SCHEMBL15712876	0.79	PGR (0.54)	DHODHMPOKMT2AMEN1LMNA
	SCHEMBL15712705	0.78	HPD (0.46)	DHODHMPOKMT2AMEN1LMNA
	SCHEMBL15712717	0.78	KDM4E (0.48)	DHODHMPOKMT2AMEN1LMNA
	SCHEMBL15712546	0.78	MAPT (0.53)	DHODHMPOKMT2AMEN1POLB
	SCHEMBL15712331	0.77	ERBB2 (0.55)	DHODHMPOKMT2AMEN1LMNA
	SCHEMBL15712832	0.77	ERBB2 (0.53)	DHODHMPOKMT2AMEN1LMNA
	SCHEMBL15712322	0.76	MPO (0.45)	DHODHMPOKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.