Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17972755 | 0.71 | L3MBTL1 (0.50) | TDP1POLBSMN1; SMN2GLAL3MBTL1 | |
| SCHEMBL8231979 | 0.69 | HDAC4 (0.44) | TDP1POLBSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL1231048 | 0.66 | L3MBTL1 (0.44) | TDP1POLBSMN1; SMN2GLAL3MBTL1 | |
| SCHEMBL29682135 | 0.65 | L3MBTL1 (0.80) | TDP1POLBSMN1; SMN2GLAL3MBTL1 | |
| SCHEMBL340762 | 0.65 | L3MBTL1 (0.80) | TDP1POLBSMN1; SMN2GLAL3MBTL1 | |
| SCHEMBL13616955 | 0.64 | PTGDR2 (0.54) | TDP1POLBSMN1; SMN2GLAL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL28240461 | 0.64 | L3MBTL1 (0.77) | TDP1POLBSMN1; SMN2GLAL3MBTL1 | |
| SCHEMBL8528987 | 0.62 | PTGDR2 (0.55) | TDP1L3MBTL1PKMPTGDR2MAPT | |
| SCHEMBL14060872 | 0.62 | L3MBTL1 (0.47) | TDP1POLBSMN1; SMN2GLAL3MBTL1 | |
| SCHEMBL3044855 | 0.62 | PTGDR2 (0.79) | TDP1POLBGLAL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453652-B2 | Di-macrocycles | LUMIPHORE, INC. (US) | 2022-09-27 | — | — | US | disclosed |
| EP-2920157-B1 | DI-MACROCYCLES | LUMIPHORE INC (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-2920157-B1 | DI-MACROCYCLES | LUMIPHORE INC (US) | 2019-09-11 | — | — | EP | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| EP-2920157-A1 | DI-MACROCYCLES | Lumiphore, Inc. (US) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014078690-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| WO-2014078690-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221971-A1 | DI-MACROCYCLES | DLD, NDC1, MCL1 | TDP1 2908/4885POLB 1220/4885SMN1; SMN2 3304/4885 |
| US-11453652-B2 | Di-macrocycles | DLD, NDC1, MCL1 | TDP1 2908/4885POLB 1220/4885SMN1; SMN2 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.