Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | HAAO | P46952 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SELL | P14151 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016842 | 0.70 | KDM4E (0.46) | HDAC4HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL2788070 | 0.67 | IDH1 (0.62) | HDAC4HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL7828749 | 0.65 | ALDH1A1 (0.48) | HDAC8ALDH1A1ALOX15POLBAPEX1 | |
| SCHEMBL29445717 | 0.65 | CYP1A2 (0.61) | HDAC8CYP1A2ALDH1A1ALOX15SELL | |
| SCHEMBL22989 | 0.65 | CYP1A2 (0.61) | HDAC8CYP1A2ALDH1A1ALOX15SELL | |
| SCHEMBL1988762 | 0.65 | CYP1A2 (0.61) | HDAC8CYP1A2ALDH1A1ALOX15SELL | |
| Hydrochloric Acid SCHEMBL17597735 | 0.64 | ALDH1A1 (0.46) | HDAC8ALDH1A1ALOX15POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL17595031 | 0.64 | ALDH1A1 (0.46) | HDAC8ALDH1A1ALOX15POLBAPEX1 | |
| SCHEMBL12168771 | 0.64 | HAAO (0.50) | HAAOCYP1A2ALDH1A1POLBTDP1 | |
| SCHEMBL20593880 | 0.64 | HAAO (0.50) | HAAOCYP1A2ALDH1A1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12440584-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | LUMIPHORE, INC. (US) | 2025-10-14 | — | — | US | disclosed |
| US-20250090696-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2025-03-20 | — | — | US | disclosed |
| US-11951188-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | LUMIPHORE, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2024-02-29 | — | — | US | disclosed |
| US-11603371-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | LUMIPHORE, INC. (US) | 2023-03-14 | — | — | US | disclosed |
| US-11453652-B2 | Di-macrocycles | LUMIPHORE, INC. (US) | 2022-09-27 | — | — | US | disclosed |
| EP-3762042-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | Lumiphore, Inc. (US) | 2021-01-13 | — | — | EP | disclosed |
| US-20200405887-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2020-12-31 | — | — | US | disclosed |
| EP-2816038-A1 | Hopo chelators | Lumiphore, Inc. (US) | 2014-12-24 | — | — | EP | disclosed |
| EP-2470513-B1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE INC (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-2470513-B1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE INC (US) | 2014-10-08 | — | — | EP | disclosed |
| WO-2014078690-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| US-20120214253-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120214253-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120214253-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| EP-2470513-A1 | MACROCYCLIC HOPO CHELATORS | Lumiphore, Inc. (US) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011025790-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. (US) | 2011-03-03 | — | — | WO | disclosed |
| WO-2011025790-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. (US) | 2011-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11453652-B2 | Di-macrocycles | DLD, NDC1, MCL1 | HDAC4 2900/4885HDAC1 1350/4885HDAC7 2702/4885 |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | HDAC4 2404/4885HDAC1 949/4885HDAC7 2522/4885 |
| US-12440584-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | TFRC, CLTC, SLC39A3 | HDAC4 2404/4885HDAC1 949/4885HDAC7 2522/4885 |
| US-11603371-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | TFRC, CLTC, SLC39A3 | HDAC4 2404/4885HDAC1 949/4885HDAC7 2522/4885 |
| US-20250090696-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | HDAC4 2404/4885HDAC1 949/4885HDAC7 2522/4885 |
| US-20120214253-A1 | MACROCYCLIC HOPO CHELATORS | PHPT1, SSB, CD69 | HDAC4 3413/4885HDAC1 2580/4885HDAC7 2522/4885 |
| US-20200405887-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | HDAC4 2404/4885HDAC1 949/4885HDAC7 2522/4885 |
| US-11951188-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | TFRC, CLTC, SLC39A3 | HDAC4 2404/4885HDAC1 949/4885HDAC7 2522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.