SCHEMBL157168

SCHEMBL157168

[NH]c1cccc2cc(S(=O)(=O)O)ccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 4/20 0.55
ALDH1A1 P00352 6/20 0.49
HSD17B10 Q99714 4/20 0.49
CYP2C9 P11712 4/20 0.49
CYP2C19 P33261 2/20 0.49
CYP1A2 P05177 4/20 0.47
HIF1A Q16665 2/20 0.47
TSHR P16473 2/20 0.47
PTPRA P18433 1/20 0.47
PTPRB P23467 1/20 0.47
RAPGEF4 Q8WZA2 1/20 0.47
RHOA P61586 1/20 0.46
TDP1 Q9NUW8 4/20 0.43
NSD2 O96028 3/20 0.42
DUSP3 P51452 2/20 0.42
PTPN5 P54829 2/20 0.42
PTPN11 Q06124 2/20 0.42
SNCA P37840 2/20 0.42
NT5E P21589 1/20 0.42
KMT2A Q03164 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156485 0.86 ALDH1A1 (0.49) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL1807954 0.82 LMNA (0.56) KMT2AMEN1
SCHEMBL343180 0.81 CASP6 (0.53) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL29889996 0.81 CASP6 (0.58) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL31255683 0.81 CASP6 (0.58) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL429785 0.81 CASP6 (0.58) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL10864839 0.80 CASP6 (0.56) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL11155537 0.80 CASP6 (0.56) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL3147761 0.80 CASP6 (0.56) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL5346617 0.80 CASP6 (0.56) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107012695-B Penetrating fluid for ink jet textile printing, ink jet textile printing method, and ink jet textile printing apparatus 精工爱普生株式会社 2020-08-07 CN disclosed
EP-2441806-B1 PORPHYRAZINE COLORING MATTER, INK COMPOSITION, RECORDING METHOD, AND COLORED OBJECT NIPPON KAYAKU KK (JP) 2017-09-06 EP disclosed
EP-2463345-B1 Ink composition, recording method using the same and recorded material SEIKO EPSON CORP (JP) 2017-01-18 EP disclosed
EP-3015516-A1 INK COMPOSITION, INK JET RECORDING METHOD USING SAME, AND COLORED MATERIAL Nippon Kayaku Kabushiki Kaisha (JP) 2016-05-04 EP disclosed
EP-2420538-B1 PORPHYRAZINE DYE, INK COMPOSITION CONTAINING SAME, AND COLORED BODY NIPPON KAYAKU KK (JP) 2015-04-22 EP disclosed
US-8876273-B2 Ink composition, ink jet recording method using the same and recorded material SEIKO EPSON CORPORATION (JP) 2014-11-04 US disclosed
US-8857965-B2 Ink compostion, recording method using the same and recorded material SEIKO EPSON CORPORATION (JP) 2014-10-14 US disclosed
US-8790458-B2 Ink set and droplet ejection apparatus using the ink set SEIKO EPSON CORPORATION (JP) 2014-07-29 US disclosed
US-8657433-B2 Porphyrazine coloring matter, ink composition, recording method, and colored object NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-02-25 US disclosed
EP-2206747-B1 ANTHRAPYRIDONE COMPOUND, SALT THEREOF, MAGENTA INK COMPOSITION AND COLORED BODY NIPPON KAYAKU KK (JP) 2013-11-06 EP disclosed
US-20100221502-A1 Anthrapyridone Compound and Salt Thereof, Magenta Ink Composition Containing the Anthrapyridone Compound, and Colored Article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-09-02 US disclosed
US-20100209678-A1 ANTHRAPYRIDONE COMPOUND OR SALT THEREOF, MAGENTA INK COMPOSITION AND COLORED PRODUCT NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-08-19 US disclosed
EP-2206747-A1 ANTHRAPYRIDONE COMPOUND, SALT THEREOF, MAGENTA INK COMPOSITION AND COLORED BODY Nippon Kayaku Kabushiki Kaisha (JP) 2010-07-14 EP disclosed
US-20100112218-A1 NOVEL PORPHYRAZINE COLORING MATTER, INK, INK SET, AND COLORED PRODUCT NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-05-06 US disclosed
EP-2128202-A1 NOVEL PORPHYRAZINE DYE, INK, INK SET, AND COLORED MATERIAL Nippon Kayaku Kabushiki Kaisha (JP) 2009-12-02 EP disclosed
US-7223301-B2 Anthrapyridone compound, water-based magenta ink composition and inkjet recording method NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-05-29 US disclosed
US-20060219131-A1 Anthrapyridone compound, aqueous magenta ink composition and inkjet recording method NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-10-05 US disclosed
EP-1626069-A1 ANTHRAPYRIDONE COMPOUND, AQUEOUS MAGENTA INK COMPOSITION AND INKJET RECORDING METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-02-15 EP disclosed
EP-1315695-B1 BENZENE TRICARBOXYLIC ACID AMIDES AS INSULIN RECEPTOR ACTIVATORS TELIK INC (US) 2005-07-13 EP disclosed
US-6600069-B2 Insulin receptor kinase activators; treating hyperglycemia; 4-((3,5-bis(N-(4-sulfophenyl)carbamoyl)phenyl)carbonylamino)-benzenesulfonic acid, for example TELIK, INC. 2003-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100209678-A1 ANTHRAPYRIDONE COMPOUND OR SALT THEREOF, MAGENTA INK COMPOSITION AND COLORED PRODUCT RB1, ATXN2, ATXN10 CASP6 2834/4885ALDH1A1 1925/4885HSD17B10 1677/4885
US-20100221502-A1 Anthrapyridone Compound and Salt Thereof, Magenta Ink Composition Containing the Anthrapyridone Compound, and Colored Article ABL1, ATXN2L, ANXA7 CASP6 2033/4885ALDH1A1 2170/4885HSD17B10 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.