Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12520764 | 0.98 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL17239956 | 0.69 | PNMT (0.36) | — | |
| SCHEMBL5021296 | 0.67 | SIGMAR1 (0.50) | SIGMAR1 | |
| SCHEMBL17240236 | 0.65 | NNMT (0.32) | — | |
| SCHEMBL154827 | 0.65 | SIGMAR1 (0.40) | SIGMAR1 | |
| SCHEMBL17239990 | 0.65 | — | — | |
| SCHEMBL15067 | 0.62 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL5048733 | 0.62 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL20554291 | 0.62 | — | — | |
| SCHEMBL5021300 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2035 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050970-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS, INC. | 2017-02-23 | — | — | US | claimed |
| WO-2024151489-A1 | PHARMACEUTICAL PYRIDYL COMPOSITIONS AND METHODS FOR USE | Unicycive Therapeutics Inc. (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | PURDUE RESEARCH FOUNDATION | 2024-07-18 | — | — | US | disclosed |
| US-20240239797-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
| US-12036211-B2 | Nicorandil derivatives | Unicycive Therapeutics Inc. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12036078-B2 | Oral products and methods for producing the same | PolySpectra, Inc. (US) | 2024-07-16 | — | — | US | disclosed |
| WO-2024148191-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| US-12029708-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030870-B2 | Benzamides of pyrazolylamino-pyrimidinyl derivatives, and compositions and methods thereof | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-07-09 | — | — | US | disclosed |
| CN-118290403-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2009018338-A2 | PHOSPHORYLATED PYRONE ANALOGS AND METHODS | LIMERICK BIOPHARMA, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009018326-A2 | SOLUBLE PYRONE ANALOGS METHODS AND COMPOSITIONS | LIMERICK BIOPHARMA, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009005794-A2 | ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2009-01-08 | — | — | WO | disclosed |
| US-20080316678-A1 | Nanoparticle ultracapacitor | DAIS ANALYTIC CORPORATION | 2008-12-25 | — | — | US | disclosed |
| WO-2008141179-A1 | MOLECULE SULFONATION PROCESS | AEGIS BIOSCIENCES LLP (US) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008131368-A2 | STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| US-20080227789-A1 | DIAMINOTHIAZOLES USEFUL AS AXL INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-18 | — | — | US | disclosed |
| WO-2008089484-A1 | MULTI-PHASE SELECTIVE MASS TRANSFER THROUGH A MEMBRANE | DAIS ANALYTIC CORPORATION (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008080134-A2 | 4-AMIN0-2- (HETERO) ARYLAMINO-5- (HETERO) ARYLTHIAZOLES USEFUL AS AXL INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008039779-A2 | ENHANCED HVAC SYSTEM AND METHOD | DAIS ANALYTIC CORPORATION (US) | 2008-04-03 | — | — | WO | disclosed |