SCHEMBL157221

SCHEMBL157221

CC(C)c1[c]ccc(C(C)C)c1C(C)C

nearest known ligand 0.30

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
GABRA1 P14867 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRG2 P18507 1/20 0.30
PTGS1 P23219 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30
HTR2B P41595 1/20 0.30
GABRA2 P47869 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14157332 0.79 GABRA1 (0.35) FAAHCA1CA2LMNACYP1A2
SCHEMBL7037210 0.77 GABRA1 (0.33) FAAHCA1CA2LMNACYP1A2
SCHEMBL9244695 0.76 GABRA1 (0.48) FAAHCA1CA2LMNACYP1A2
SCHEMBL4632329 0.76 GABRA1 (0.38) FAAHCA1CA2LMNACYP1A2
SCHEMBL27506728 0.76 EIF4A3 (0.30)
SCHEMBL9245578 0.76 GABRA1 (0.31) GABRA1GABRB1
SCHEMBL2138025 0.76
SCHEMBL3236614 0.76 GABRA1 (0.31) GABRA1GABRB1
SCHEMBL9672407 0.76 AHR (0.32) GABRA1GABRB2
SCHEMBL2138031 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 546 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118255642-A Asymmetric synthesis method and application of chiral primary amine compound 中国科学院深圳先进技术研究院 2024-06-28 CN claimed
WO-2024124895-A1 SYNTHESIS METHOD FOR CHIRAL PHOSPHORIC ACID CATALYST 上海泰坦科技股份有限公司 2024-06-20 WO claimed
CN-118184915-A Propylene and alpha-olefin multi-block copolymer elastomer material, and preparation method and application thereof 天津大学 2024-06-14 CN claimed
EP-4370500-A1 AROMATIC CARBODIIMIDES, PROCESS FOR THE PREPARATION AND USE THEREOF LANXESS Deutschland GmbH (DE) 2024-05-22 EP claimed
WO-2024098464-A1 PREPARATION METHOD FOR OPTICALLY PURE α-ARYL CHIRAL AMINE COMPOUND, AND USE THEREOF 深圳先进技术研究院 2024-05-16 WO claimed
CN-118026793-A Preparation method and application of optically pure alpha-aryl chiral amine compound 深圳先进技术研究院 2024-05-14 CN claimed
CN-117831652-A Prediction method of olefin hydroformylation positive-to-negative ratio 上海华谊控股集团有限公司 2024-04-05 CN claimed
CN-117616009-A Aromatic carbodiimide, method for producing same and use thereof 朗盛德国有限责任公司 2024-02-27 CN claimed
EP-4244202-A1 METHOD OF SYNTHESIS University of Durham (GB) 2023-09-20 EP claimed
US-20230292591-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US claimed
US-20030083517-A1 Methods of preparing sulfinamides and sulfoxides APSINTERM LLC 2003-05-01 US claimed
EP-1098651-B1 NOVEL UROKINASE INHIBITORS WILEX AG (DE) 2003-01-08 EP claimed
WO-2002083608-A2 METHODS OF PREPARING SULFINAMIDE AND SULFOXIDES APSINTERM LLC (US) 2002-10-24 WO claimed
EP-1021449-B1 HYDROXYACETIC ESTER DERIVATIVES, PREPARATION METHOD AND USE AS SYNTHESIS INTERMEDIATES SANOFI SYNTHELABO (FR) 2002-01-02 EP claimed
EP-0649877-B1 Self-lubricating mixtures GE BAYER SILICONES GMBH & CO (DE) 2001-03-28 EP claimed
EP-1021449-A1 HYDROXYACETIC ESTER DERIVATIVES, PREPARATION METHOD AND USE AS SYNTHESIS INTERMEDIATES SANOFI-SYNTHELABO (FR) 2000-07-26 EP claimed
WO-1999018110-A1 HYDROXYACETIC ESTER DERIVATIVES, PREPARATION METHOD AND USE AS SYNTHESIS INTERMEDIATES SANOFI-SYNTHELABO (FR) 1999-04-15 WO claimed
EP-0071150-B1 SULFIMINES, THEIR SALTS AND THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1985-07-03 EP claimed
US-4507479-A Color-forming sulfonamidodiphenylamine dye precursor that produces phenazine dye EASTMAN KODAK COMPANY (US) 1985-03-26 US claimed
US-3936410-A Triaryl phosphate ester plasticizers for polyvinyl chloride compositions FMC CORPORATION (US) 1976-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230292591-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES POF1B, FOSB, OSBP FAAH 1526/4885CA1 2547/4885CA2 2862/4885
US-20030083517-A1 Methods of preparing sulfinamides and sulfoxides STS, TST, CBS FAAH 2049/4885CA1 1528/4885CA2 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.