Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12269929 | 0.88 | CCR1 (0.54) | COMTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL30797999 | 0.87 | ALDH1A1 (0.41) | COMTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL20817544 | 0.87 | ALDH1A1 (0.41) | COMTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL18422770 | 0.87 | ALDH1A1 (0.41) | COMTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL16775698 | 0.84 | COMT (0.39) | COMTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL23087554 | 0.82 | COMT (0.38) | COMTALDH1A1KDM4ELMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29289853 | 0.82 | IRAK4 (0.45) | COMTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL29735282 | 0.82 | COMT (0.38) | COMTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL31704800 | 0.81 | KDM4E (0.48) | COMTALDH1A1KDM4ELMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31098626 | 0.81 | IRAK4 (0.38) | COMTALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920186-B1 | NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION | UNIV HONG KONG (CN) | 2018-06-27 | — | — | EP | disclosed |
| US-8828984-B2 | Gold(III) complexes containing N-heterocyclic carbene ligand, synthesis, and their applications in cancer treatment and thiol detection | THE UNIVERSITY OF HONG KONG (CN) | 2014-09-09 | — | — | US | disclosed |
| US-8828984-B2 | Gold(III) complexes containing N-heterocyclic carbene ligand, synthesis, and their applications in cancer treatment and thiol detection | THE UNIVERSITY OF HONG KONG (CN) | 2014-09-09 | — | — | US | disclosed |
| WO-2014075394-A1 | NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION | THE UNIVERSITY OF HONG KONG (CN) | 2014-05-22 | — | — | WO | disclosed |
| US-20140142080-A1 | NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION | UNIVERSITY OF HONG KONG (CN) | 2014-05-22 | — | — | US | disclosed |
| US-20140142080-A1 | NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION | UNIVERSITY OF HONG KONG (CN) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142080-A1 | NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION | TXNRD3, TXNRD1, TXN | COMT 3017/4885ALDH1A1 410/4885KDM4E 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.