Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.40 |
| ▸ | ATP4A | P20648 | 2/20 | 0.39 |
| ▸ | ATP4B | P51164 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496560 | 0.93 | HPGD (0.41) | RXRAATMATP4AATP4BNPC1 | |
| SCHEMBL4496071 | 0.88 | KMT2A (0.38) | HPGDSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL1573301 | 0.88 | KMT2A (0.38) | HPGDSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL1572906 | 0.84 | DDB1 (0.36) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL1572736 | 0.84 | KMT2A (0.35) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1573244 | 0.84 | CTSV (0.39) | RXRAATMPTGER1ATP4AATP4B | |
| SCHEMBL1573188 | 0.84 | ALDH1A1 (0.35) | ATMNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1572804 | 0.84 | KMT2A (0.37) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL4496523 | 0.83 | CTSD (0.39) | MEN1KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL4507727 | 0.83 | PLA2G1B (0.40) | HPGDSMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018165-B1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI AVENTIS (FR) | 2011-04-13 | — | — | EP | disclosed |
| EP-2018165-A1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | Sanofi-Aventis (FR) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007080325-A1 | FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI-AVENTIS (FR) | 2007-07-19 | — | — | WO | disclosed |