Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 9/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CBX7 | O95931 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.31 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501050 | 0.92 | MEN1 (0.36) | DDB1CRBNMEN1KMT2AMAPT | |
| SCHEMBL1573301 | 0.85 | KMT2A (0.38) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL4496071 | 0.85 | KMT2A (0.38) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL1572836 | 0.84 | RXRA (0.41) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL13918690 | 0.83 | MEN1 (0.38) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL4496523 | 0.83 | CTSD (0.39) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL4507727 | 0.83 | PLA2G1B (0.40) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL1572736 | 0.81 | KMT2A (0.35) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL1572804 | 0.81 | KMT2A (0.37) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL1573188 | 0.79 | ALDH1A1 (0.35) | MEN1KMT2AMAPTLMNAPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018165-B1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI AVENTIS (FR) | 2011-04-13 | — | — | EP | disclosed |