SCHEMBL15737338

SCHEMBL15737338

CO[Si](O)(OC)c1ccc(F)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
PDGFRB P09619 1/20 0.32
PDGFRA P16234 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
ALDH1A1 P00352 2/20 0.31
NFE2L2 Q16236 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15733540 0.85 CYP11B1 (0.41) PDGFRBPDGFRAALDH1A1
SCHEMBL27959607 0.83 CES2 (0.34) CES2CES1PDGFRBPDGFRAALDH1A1
SCHEMBL15738573 0.79 CHRNA1 (0.32) CES2CES1
SCHEMBL15735663 0.79 HPGD (0.37) CES2CES1ALDH1A1HPGDTSHR
SCHEMBL15737670 0.78 PDGFRB (0.33) CES2CES1PDGFRBPDGFRANFE2L2
SCHEMBL15735880 0.78 TUBB1 (0.36) CES2CES1
SCHEMBL15738130 0.77 IDO1 (0.33) CES2CES1PDGFRBPDGFRANFE2L2
SCHEMBL15736625 0.77 IDO1 (0.33) CES2CES1PDGFRBPDGFRANFE2L2
SCHEMBL15733634 0.76 PTGS2 (0.37)
SCHEMBL15734871 0.76 ACHE (0.36) CES2CES1MAPK1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
CN-103848859-A Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same SHINETSU CHEMICAL CO 2014-06-11 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed