SCHEMBL15734827

SCHEMBL15734827

OC(O)(O[SiH3])c1ccc(-c2ccc(F)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
KIF11 P52732 8/20 0.36
HSD17B1 P14061 3/20 0.36
HSD17B2 P37059 3/20 0.36
TRPA1 O75762 1/20 0.35
KCNN4 O15554 1/20 0.33
NOTUM Q6P988 1/20 0.33
PDGFRB P09619 1/20 0.32
PDGFRA P16234 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15734486 0.86 ANPEP (0.35) KIF11
SCHEMBL15735195 0.85 KCNN4 (0.40) KCNN4
SCHEMBL15735144 0.81 USP2 (0.39) CYP17A1KIF11KCNN4KDM4E
SCHEMBL15738775 0.81 APP (0.35) KIF11PTGS1PTGS2
SCHEMBL15733415 0.80 RXRA (0.36) CYP17A1CYP11B1KIF11
SCHEMBL15735449 0.79 TAAR1 (0.53) CYP17A1CYP11B1CYP11B2HSD17B1HSD17B2
SCHEMBL15735778 0.79 CYP17A1 (0.41) CYP17A1CYP11B1CYP11B2KIF11HSD17B1
SCHEMBL15733760 0.77 TNKS (0.35)
SCHEMBL15735018 0.77 KIF11 (0.54) KIF11
SCHEMBL15733997 0.75 RXRA (0.50) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed