SCHEMBL15735449

SCHEMBL15735449

OC(O)(O[SiH3])c1ccc(-c2cccc(F)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.53
ESR2 Q92731 1/20 0.53
PTPN1 P18031 1/20 0.53
CYP11B2 P19099 2/20 0.41
CYP17A1 P05093 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP11B1 P15538 1/20 0.41
PDK2 Q15119 1/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
NT5E P21589 2/20 0.38
MAP4K4 O95819 2/20 0.38
MMP1 P03956 2/20 0.37
MMP2 P08253 2/20 0.37
MMP3 P08254 2/20 0.37
MMP7 P09237 2/20 0.37
MMP9 P14780 2/20 0.37
MMP13 P45452 2/20 0.37
DCLRE1B Q9H816 1/20 0.37
PAX8 Q06710 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15733415 0.84 RXRA (0.36) TAAR1ESR2PTPN1CYP17A1CYP11B1
SCHEMBL15735144 0.82 USP2 (0.39) PTPN1CYP17A1CYP3A4
SCHEMBL15734993 0.82 KIF11 (0.49) PTPN1MMP1MMP2MMP9MMP13
SCHEMBL15734515 0.80 KCNN4 (0.47) TAAR1ESR2PTPN1
SCHEMBL15738692 0.80 PTPN1 (0.49) TAAR1ESR2PTPN1CYP11B2CYP17A1
SCHEMBL15734827 0.79 CYP17A1 (0.38) CYP11B2CYP17A1CYP11B1HSD17B1HSD17B2
SCHEMBL15733671 0.76 TAAR1 (0.46) TAAR1ESR2PTPN1CYP11B2CYP17A1
SCHEMBL15734486 0.76 ANPEP (0.35) ESR2
SCHEMBL15737186 0.76 RAB9A (0.43) CYP3A4
SCHEMBL15735093 0.75 TTR (0.41) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed