SCHEMBL15733997

SCHEMBL15733997

OC(O)(O[SiH3])c1ccc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RXRA P19793 10/20 0.50
RXRB P28702 9/20 0.50
RXRG P48443 9/20 0.50
KIF11 P52732 7/20 0.42
CES2 O00748 1/20 0.38
BACE1 P56817 1/20 0.37
BACE2 Q9Y5Z0 1/20 0.37
NAAA Q02083 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735018 0.89 KIF11 (0.54) KIF11CES2
SCHEMBL15734993 0.85 KIF11 (0.49) KIF11CES2BACE1
SCHEMBL15738825 0.82 CES2 (0.48) RXRARXRBRXRGCES2
SCHEMBL15733955 0.82 KIF11 (0.43) KIF11CES2
SCHEMBL15733415 0.80 RXRA (0.36) RXRARXRBRXRGKIF11
SCHEMBL15734273 0.79 RXRA (0.46) RXRARXRBRXRGKIF11NAAA
SCHEMBL15734486 0.79 ANPEP (0.35) KIF11
SCHEMBL15735144 0.77 USP2 (0.39) KIF11
SCHEMBL15738537 0.76 CES2 (0.50) KIF11CES2
SCHEMBL15734827 0.75 CYP17A1 (0.38) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed