SCHEMBL15734945

SCHEMBL15734945

CC[Si](OC)(OC)c1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.38
NOTUM Q6P988 1/20 0.35
TACR1 P25103 3/20 0.33
CACNA1H O95180 2/20 0.33
CES2 O00748 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
PTPN5 P54829 1/20 0.33
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
F2RL3 Q96RI0 1/20 0.31
IKBKB O14920 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735504 0.84 RXRA (0.44) IDO1HSP90AA1HSP90AB1CTSSCTSK
SCHEMBL15733740 0.82 IDO1 (0.41) IDO1MAPT
SCHEMBL15736944 0.82 NR1H2 (0.41) IDO1CES2NR1H2NR1H3
SCHEMBL15738223 0.80 IDO1 (0.38) IDO1NOTUMTACR1CACNA1HCES2
SCHEMBL15737258 0.77 KIF11 (0.48) NR1H2NR1H3
SCHEMBL7049416 0.77 IDO1 (0.38) IDO1NOTUMTACR1CACNA1HCES2
SCHEMBL15738736 0.76 IDO1 (0.35) IDO1NOTUMCACNA1HCES2HSP90AA1
SCHEMBL704447 0.75 ESR1 (0.37) NR1H2NR1H3
SCHEMBL15733327 0.75 IDO1 (0.36) IDO1NOTUMCACNA1HCES2HSP90AA1
SCHEMBL15738264 0.75 NOTUM (0.37) IDO1NOTUMCACNA1HCES2HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed