SCHEMBL15733740

SCHEMBL15733740

CC[Si](OC)(OC)c1cccc(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAPK1 P28482 2/20 0.40
HTR2A P28223 2/20 0.40
HTR2B P41595 2/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
HTR2C P28335 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 1/20 0.40
CYP1A2 P05177 2/20 0.39
PNMT P11086 1/20 0.39
BRD9 Q9H8M2 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
ADRA2C P18825 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
DRD3 P35462 1/20 0.39
OPRK1 P41145 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735382 0.84 MAOB (0.49) L3MBTL1MAPTALDH1A1GAAATM
SCHEMBL15736900 0.83 LMNA (0.42) IDO1L3MBTL1MAPK1HTR2AHTR2B
SCHEMBL15734945 0.82 IDO1 (0.38) IDO1MAPT
SCHEMBL7723295 0.80 MAPK1 (0.44) IDO1L3MBTL1MAPK1HTR2AHTR2B
SCHEMBL18234136 0.80 TSHR (0.47) IDO1L3MBTL1MAPK1HTR2AHTR2B
SCHEMBL15736944 0.80 NR1H2 (0.41) IDO1MAPK1LMNATSHRCYP1A2
SCHEMBL15733442 0.79 L3MBTL1 (0.40) IDO1L3MBTL1MAPK1HTR2AHTR2B
SCHEMBL15736663 0.79 L3MBTL1 (0.40) IDO1L3MBTL1MAPK1HTR2AHTR2B
SCHEMBL15734300 0.79 ACHE (0.38) IDO1TAAR1
SCHEMBL15736195 0.79 L3MBTL1 (0.42) IDO1L3MBTL1MAPK1HTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed