SCHEMBL15736859

SCHEMBL15736859

CCO[Si](OC)(OC)c1ccc(-c2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.46
NR1H4 Q96RI1 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 3/20 0.43
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.43
KDM1A O60341 1/20 0.42
KIF11 P52732 1/20 0.41
ATM Q13315 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
BACE1 P56817 1/20 0.40
DYRK3 O43781 1/20 0.40
CCNT1 O60563 1/20 0.40
CCNA2 P20248 1/20 0.40
CDK2 P24941 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738782 0.97 MAOB (0.46) MAOBNR1H4NPSR1ALDH1A1GAA
SCHEMBL15733957 0.93 MAOB (0.49) MAOBNR1H4NPSR1ALDH1A1GAA
SCHEMBL15737457 0.88 MAOB (0.49) MAOBNR1H4NPSR1ALDH1A1GAA
SCHEMBL15735964 0.87 RXRA (0.41) NR1H4NPSR1KIF11BACE1NAAA
SCHEMBL15733442 0.85 L3MBTL1 (0.40) NR1H4NPSR1ALDH1A1GAAKDM4E
SCHEMBL15736073 0.85 KIF11 (0.44) MAOBKDM4EHPGDKIF11MEN1
SCHEMBL15735615 0.84 RXRA (0.41) KIF11BACE1NAAACTSSCTSK
SCHEMBL15734692 0.83 MAOB (0.48) MAOBNR1H4NPSR1ALDH1A1GAA
SCHEMBL15735017 0.83 TAAR1 (0.45)
SCHEMBL15750880 0.83 MAOB (0.48) MAOBNR1H4NPSR1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed