SCHEMBL15735964

SCHEMBL15735964

CCO[Si](OC)(OC)c1ccc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 9/20 0.41
RXRB P28702 9/20 0.41
RXRG P48443 8/20 0.41
BACE1 P56817 1/20 0.36
BACE2 Q9Y5Z0 1/20 0.36
NAAA Q02083 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35
NR1H4 Q96RI1 1/20 0.33
KDR P35968 1/20 0.33
KIF11 P52732 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735615 0.97 RXRA (0.41) RXRARXRBRXRGBACE1BACE2
SCHEMBL15737418 0.92 RXRA (0.44) RXRARXRBRXRGBACE1BACE2
SCHEMBL15736073 0.89 KIF11 (0.44) HSP90AA1KDRKIF11
SCHEMBL15733521 0.87 RXRA (0.47) RXRARXRBRXRGBACE1BACE2
SCHEMBL15736859 0.87 MAOB (0.46) BACE1NAAANR1H4KIF11NPSR1
SCHEMBL15737478 0.86 KIF11 (0.44) HSP90AA1KDRKIF11
SCHEMBL15738736 0.85 IDO1 (0.35) HSP90AA1HSP90AB1NPSR1IDO1CTSS
SCHEMBL15738782 0.84 MAOB (0.46) BACE1NAAANR1H4KIF11NPSR1
SCHEMBL15738099 0.84 HPGD (0.39) HSP90AA1KIF11NPSR1IDO1MAPK1
SCHEMBL15734656 0.81 FGFR1 (0.35) RXRARXRBRXRGBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed