Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573729 | 0.82 | HDAC1 (0.39) | HSD11B1MEN1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL1573664 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1KDM4EFAAH | |
| SCHEMBL1573842 | 0.78 | ACHE (0.47) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL1574012 | 0.77 | HSP90AA1 (0.44) | ELANERORCMEN1KMT2AALDH1A1 | |
| SCHEMBL5641531 | 0.75 | FAAH (0.57) | F2KMT2AFAAHMGLLGAA | |
| SCHEMBL1573652 | 0.74 | HPGD (0.39) | ELANERORCALDH1A1KDM4ENPC1 | |
| SCHEMBL1574211 | 0.71 | NOTUM (0.50) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL11009351 | 0.69 | ELANE (0.64) | ELANEF2PLAURORCKMT2A | |
| SCHEMBL11008441 | 0.69 | IDO1 (0.44) | ELANEKMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL5120296 | 0.68 | ELANE (0.56) | ELANEF2PLAUALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-B1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-04-13 | — | — | EP | disclosed |
| CN-1914180-A | Indazole derivatives as hormone sensitive lipase inhibitors | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-02-14 | — | — | CN | disclosed |