Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573892 | 0.89 | ALDH1A1 (0.46) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL1573947 | 0.86 | GAA (0.46) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL1573535 | 0.85 | GAA (0.45) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL1573835 | 0.85 | GAA (0.45) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL1574523 | 0.85 | ALDH1A1 (0.46) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL1573823 | 0.85 | GAA (0.45) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL1574490 | 0.83 | LIPE (0.50) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL1573881 | 0.83 | GAA (0.43) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL1573600 | 0.82 | RAB9A (0.58) | HPGDALDH1A1TP53NPC1RAB9A | |
| SCHEMBL1576556 | 0.82 | ALDH1A1 (0.45) | HPGDALDH1A1SMN1; SMN2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-B1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-04-13 | — | — | EP | disclosed |