Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573883 | 0.90 | GAA (0.41) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1573836 | 0.83 | GAA (0.36) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1573937 | 0.83 | LIPE (0.38) | GAALIPE | |
| SCHEMBL1573859 | 0.82 | GAA (0.41) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1574115 | 0.81 | GAA (0.41) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1573819 | 0.80 | GAA (0.40) | GAAALDH1A1HPGDTP53NPC1 | |
| SCHEMBL1573815 | 0.80 | GAA (0.43) | GAAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1573763 | 0.79 | SMN1; SMN2 (0.42) | GAAALDH1A1CYP2C19NPC1RAB9A | |
| SCHEMBL1573851 | 0.79 | SPR (0.37) | — | |
| SCHEMBL1573808 | 0.77 | GAA (0.47) | GAAALDH1A1NPSR1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-B1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-04-13 | — | — | EP | disclosed |