Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 10/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573851 | 0.96 | SPR (0.37) | SPR | |
| SCHEMBL1573883 | 0.92 | GAA (0.41) | LIPEGAA | |
| SCHEMBL1573846 | 0.92 | HRH3 (0.36) | SPR | |
| SCHEMBL6015472 | 0.87 | SPR (0.33) | SPR | |
| SCHEMBL1573836 | 0.87 | GAA (0.36) | LIPEGAA | |
| SCHEMBL1573785 | 0.86 | SPR (0.37) | SPR | |
| SCHEMBL1573472 | 0.85 | SPR (0.36) | SPR | |
| SCHEMBL1573885 | 0.83 | GAA (0.36) | LIPEGAA | |
| SCHEMBL1573859 | 0.82 | GAA (0.41) | LIPEGAA | |
| SCHEMBL1574115 | 0.81 | GAA (0.41) | LIPEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-B1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-04-13 | — | — | EP | disclosed |