SCHEMBL15739360

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2019199	0.89	TDP1 (0.40)	TDP1CYP2A6MEN1KMT2ARXFP1
	SCHEMBL15739430	0.88	TDP1 (0.38)	TDP1GSK3AGSK3BCYP1A2CYP2C9
	SCHEMBL22136743	0.87	PTGES (0.36)	TDP1CYP2A6MEN1KMT2ARXFP1
	SCHEMBL15739319	0.87	TDP1 (0.37)	TDP1GSK3AGSK3BCYP1A2CYP2C9
	SCHEMBL29476073	0.86	TSPO (0.41)	TDP1CYP2A6MEN1KMT2ARXFP1
	SCHEMBL490271	0.86	TSPO (0.41)	TDP1CYP2A6MEN1KMT2ARXFP1
	SCHEMBL12126569	0.85	L3MBTL1 (0.41)	CYP2A6MEN1KMT2ARXFP1ALDH1A1
	SCHEMBL20465300	0.83	CYP2A6 (0.41)	TDP1CYP2A6MEN1KMT2ARXFP1
	SCHEMBL22961223	0.83	MEN1 (0.38)	TDP1CYP2A6MEN1KMT2ARXFP1
	SCHEMBL19213874	0.83	CYP2A6 (0.43)	CYP2A6MEN1KMT2ARXFP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.