Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 12/20 | 0.36 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573851 | 0.89 | SPR (0.37) | SPRPDE10A | |
| SCHEMBL1573785 | 0.89 | SPR (0.37) | SPRPDE10A | |
| SCHEMBL1574115 | 0.88 | GAA (0.41) | — | |
| SCHEMBL1573937 | 0.85 | LIPE (0.38) | SPR | |
| SCHEMBL1573846 | 0.85 | HRH3 (0.36) | SPRPDE10A | |
| SCHEMBL1573697 | 0.82 | SCN10A (0.37) | — | |
| SCHEMBL6015472 | 0.80 | SPR (0.33) | SPR | |
| SCHEMBL1573883 | 0.76 | GAA (0.41) | — | |
| SCHEMBL1573859 | 0.76 | GAA (0.41) | — | |
| SCHEMBL4833062 | 0.75 | PDE10A (0.35) | SPRPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-B1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-04-13 | — | — | EP | disclosed |