Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.30 |
| ▸ | NPY4R | P50391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573697 | 0.88 | SCN10A (0.37) | TSHRPOLBACACBL3MBTL1JAK1 | |
| SCHEMBL1573859 | 0.83 | GAA (0.41) | TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL1573836 | 0.83 | GAA (0.36) | ACACBL3MBTL1CYP3A4SMN1; SMN2 | |
| SCHEMBL1573785 | 0.82 | SPR (0.37) | SPR | |
| SCHEMBL1574095 | 0.82 | HRH3 (0.40) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL1573883 | 0.72 | GAA (0.41) | TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL1574115 | 0.72 | GAA (0.41) | TSHRPOLBCYP3A4SMN1; SMN2 | |
| SCHEMBL1573851 | 0.72 | SPR (0.37) | SPR | |
| SCHEMBL1573819 | 0.71 | GAA (0.40) | SMN1; SMN2 | |
| SCHEMBL4836657 | 0.71 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-B1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-04-13 | — | — | EP | disclosed |