Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.40 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573859 | 0.87 | GAA (0.41) | HRH3GAASMN1; SMN2TP53 | |
| SCHEMBL1573785 | 0.83 | SPR (0.37) | — | |
| SCHEMBL1573988 | 0.82 | TSHR (0.33) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL1573883 | 0.76 | GAA (0.41) | HRH3GAASMN1; SMN2TP53 | |
| SCHEMBL1574115 | 0.75 | GAA (0.41) | HRH3GAASMN1; SMN2TP53 | |
| SCHEMBL1573815 | 0.74 | GAA (0.43) | HRH3GAASMN1; SMN2L3MBTL1TP53 | |
| SCHEMBL1573819 | 0.74 | GAA (0.40) | GAASMN1; SMN2TP53 | |
| SCHEMBL4836657 | 0.74 | KDM4E (0.33) | TP53 | |
| SCHEMBL1573851 | 0.73 | SPR (0.37) | — | |
| SCHEMBL1573472 | 0.72 | SPR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-B1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-04-13 | — | — | EP | disclosed |