Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740417 | 0.87 | SERPINE1 (0.44) | SERPINE1SLC6A9SLC6A5SMN1; SMN2MEN1 | |
| SCHEMBL15740353 | 0.86 | HRH3 (0.43) | SERPINE1SLC6A4SMN1; SMN2MEN1RECQL | |
| SCHEMBL15708168 | 0.79 | ENPP2 (0.67) | ENPP2HTR1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7253846 | 0.72 | HSD11B1 (0.47) | ENPP2HTR1ASIRT6SMN1; SMN2LMNA | |
| SCHEMBL15708172 | 0.71 | ENPP2 (0.61) | ENPP2SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL15724765 | 0.71 | MAPT (0.61) | ENPP2SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL15707965 | 0.70 | ENPP2 (0.55) | ENPP2HTR1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL15708170 | 0.69 | ENPP2 (0.55) | ENPP2SMN1; SMN2LMNAMAPTL3MBTL1 | |
| SCHEMBL15707902 | 0.68 | HNF4A (0.49) | SMN1; SMN2MEN1KMT2ALMNAHPGD | |
| SCHEMBL15707896 | 0.68 | SMN1; SMN2 (0.58) | ENPP2SERPINE1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081697-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2014-05-30 | — | — | WO | disclosed |