SCHEMBL15744200

SCHEMBL15744200

CCCCC(F)(F)C(=O)CC=O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.46
FAAH O00519 12/20 0.41
CES1 P23141 8/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 1/20 0.35
PLA2G4B P0C869 1/20 0.35
MAPT P10636 1/20 0.35
PLA2G4A P47712 1/20 0.35
BLM P54132 1/20 0.35
MGLL Q99685 1/20 0.35
PLA2G4C Q9UP65 1/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439276 0.79 CES2 (0.52) CES2FAAHCES1MEN1CYP1A2
SCHEMBL8115343 0.77 FAAH (0.56) CES2FAAHCES1MEN1CYP1A2
SCHEMBL9767600 0.73 FAAH (0.67) CES2FAAHCES1MEN1CYP1A2
SCHEMBL25122268 0.73 CES2 (0.39) CES2FAAHCES1MEN1CYP1A2
SCHEMBL18965382 0.72 CES2 (0.46) CES2FAAHCES1MEN1CYP1A2
SCHEMBL1706449 0.72 CES2 (0.54) CES2FAAHCES1MEN1CYP1A2
SCHEMBL12396593 0.72 CES2 (0.54) CES2FAAHCES1MEN1CYP1A2
SCHEMBL20654764 0.71 CES2 (0.59) CES2FAAHCES1MEN1CYP1A2
SCHEMBL10577153 0.71 CES2 (0.40) CES2FAAHCES1MEN1CYP1A2
SCHEMBL22360672 0.71 CES2 (0.40) CES2FAAHCES1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2735566-A1 Method for preparing prostaglandin derivative R-Tech Ueno, Ltd. (JP) 2014-05-28 EP disclosed