SCHEMBL15744302

SCHEMBL15744302

Fc1cc(Br)ccc1C(F)(F)Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
KDM1A O60341 5/20 0.38
KDM1B Q8NB78 1/20 0.38
KIF11 P52732 5/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPC1 O15118 3/20 0.33
LMNA P02545 3/20 0.33
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
PYCR1 P32322 1/20 0.33
CYP2A6 P11509 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56867 0.86 CYP11B2 (0.53) DGAT1CYP11B1CYP11B2KDM1AKIF11
SCHEMBL29514712 0.86 CYP11B2 (0.53) DGAT1CYP11B1CYP11B2KDM1AKIF11
SCHEMBL29988758 0.82 CYP11B1 (0.39) DGAT1CYP11B1CYP11B2KDM1AKDM1B
SCHEMBL5361521 0.82 CYP11B1 (0.39) DGAT1CYP11B1CYP11B2KDM1AKDM1B
SCHEMBL415598 0.82 CYP11B1 (0.39) DGAT1CYP11B1CYP11B2KDM1AKDM1B
SCHEMBL18285726 0.82 CYP11B1 (0.39) DGAT1CYP11B1CYP11B2KDM1AKDM1B
SCHEMBL799852 0.79 DGAT1 (0.39) DGAT1CYP11B1CYP11B2KDM1AKDM1B
SCHEMBL4468448 0.79 DGAT1 (0.39) DGAT1CYP11B1CYP11B2KDM1AKDM1B
SCHEMBL12185142 0.79 CYP11B1 (0.37) DGAT1CYP11B1CYP11B2KDM1AKDM1B
SCHEMBL18171360 0.78 ALDH1A1 (0.42) CYP11B1CYP11B2KDM1AKIF11CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
EP-2735599-A1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC Corporation (JP) 2014-05-28 EP disclosed