Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.30 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.30 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.30 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18125392 | 0.91 | CA1 (0.35) | CA2CA1ENPP2 | |
| SCHEMBL18124820 | 0.91 | CA1 (0.35) | CA2CA1ENPP2 | |
| SCHEMBL5953326 | 0.88 | CA2 (0.48) | CA2CA1ENPP2CA7CA9 | |
| SCHEMBL13308147 | 0.86 | CA1 (0.58) | CA2CA1ENPP2CA12CA7 | |
| SCHEMBL14983340 | 0.86 | ENPP2 (0.46) | CA2CA1ENPP2ORAI1ORAI2 | |
| SCHEMBL14983372 | 0.86 | TDP1 (0.46) | CA14 | |
| SCHEMBL14983341 | 0.86 | ORAI1 (0.46) | CA2CA1ENPP2CA7CA9 | |
| SCHEMBL14983349 | 0.86 | CA1 (0.46) | CA2CA1ENPP2 | |
| SCHEMBL309077 | 0.84 | CA4 (0.48) | CA2CA1ENPP2CA12CA7 | |
| SCHEMBL14985986 | 0.82 | CYP1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148596-A1 | Covalent Organic Frameworks and Methods of Making Same | CORNELL UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |