Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430197 | 0.85 | ATM (0.41) | EGFRCYP2C9ATMLMNAMEN1 | |
| SCHEMBL7444588 | 0.76 | GSK3B (0.43) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL8389861 | 0.76 | MAPK1 (0.42) | CYP2C9MAPTMEN1KMT2ATSHR | |
| SCHEMBL293418 | 0.75 | MAOA (0.32) | — | |
| SCHEMBL9772861 | 0.75 | HTR2A (0.36) | ATMMEN1KMT2A | |
| SCHEMBL9245713 | 0.74 | CYP2C9 (0.39) | CYP2C9ATMLMNAMEN1KMT2A | |
| SCHEMBL8309737 | 0.72 | IDO1 (0.35) | MEN1KMT2A | |
| SCHEMBL294641 | 0.72 | MAOA (0.31) | — | |
| SCHEMBL5605786 | 0.72 | EGFR (0.36) | EGFRCYP2C9ATMMAPTLMNA | |
| SCHEMBL21879795 | 0.70 | ATM (0.38) | CYP2C9ATMMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1306007-A1 | Compositions and method to safen crops from injury caused by uracil-substituted benzisothiazoles | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-02 | — | — | EP | claimed |
| EP-2654426-A2 | USE OF ISOTHIAZOLECARBOXAMIDES TO CREATE LATENT HOST DEFENSES IN A PLANT | Bayer Intellectual Property GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| EP-2485587-A2 | PESTICIDAL COMPOSITION FOR COATING SEED WITH A HERBICIDE | Syngenta Participations AG (CH) | 2012-08-15 | — | — | EP | disclosed |
| US-20120196748-A1 | PESTICIDAL COMPOSITION | SYNGENTA LIMITED (GB) | 2012-08-02 | — | — | US | disclosed |
| WO-2012084858-A2 | USE OF ISOTHIAZOLECARBOXAMIDES TO CREATE LATENT HOST DEFENSES IN A PLANT | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | WO | disclosed |
| WO-2011042506-A2 | PESTICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2011-04-14 | — | — | WO | disclosed |
| EP-2308297-A1 | Pesticidal composition for coating seed with a herbicide | Syngenta Participations AG (CH) | 2011-04-13 | — | — | EP | disclosed |
| EP-1306007-A1 | Compositions and method to safen crops from injury caused by uracil-substituted benzisothiazoles | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-02 | — | — | EP | disclosed |
| WO-1987004344-A1 | HYDROXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1987-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196748-A1 | PESTICIDAL COMPOSITION | DDT, PFAS, ACHE | EGFR 4155/4885CYP2C9 1048/4885ATM 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.