Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389861 | 0.80 | MAPK1 (0.42) | POLBALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL1574529 | 0.76 | EGFR (0.36) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL3430197 | 0.75 | ATM (0.41) | LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL12700339 | 0.70 | LMNA (0.58) | GSK3BSIGMAR1POLBALDH1A1LMNA | |
| SCHEMBL8309737 | 0.70 | IDO1 (0.35) | MEN1KMT2A | |
| SCHEMBL7439230 | 0.69 | GSK3B (0.46) | GSK3BSIGMAR1POLBCA1CA2 | |
| SCHEMBL16088741 | 0.67 | HSD17B10 (0.57) | GSK3BSIGMAR1POLBCA1CA2 | |
| SCHEMBL28043310 | 0.66 | KMT2A (0.65) | GSK3BPOLBCA1CA2ALDH1A1 | |
| SCHEMBL9772861 | 0.66 | HTR2A (0.36) | MEN1KMT2AHTR2ASLC6A4HRH1 | |
| SCHEMBL293418 | 0.66 | MAOA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849263-A2 | Pharmaceutical substituted propanoic acid derivatives | ELI LILLY AND COMPANY LIMITED (GB) | 1998-06-24 | — | — | EP | disclosed |