SCHEMBL15745646

SCHEMBL15745646

CCc1cc(Cc2cc(CC)c(N)c(C(C)(O)C(F)(F)F)c2)cc(C(C)(O)C(F)(F)F)c1N

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.38
HSD11B1 P28845 1/20 0.34
DHFR P00374 3/20 0.33
CFTR P13569 1/20 0.32
AR P10275 1/20 0.32
POLB P06746 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745653 0.88 AR (0.34) HSPA5DHFRAR
SCHEMBL19465268 0.86 MEN1 (0.41) HSPA5DHFRARPOLBHTT
SCHEMBL15745654 0.85 TYR (0.33) HSPA5
SCHEMBL15745662 0.82 AR (0.32) DHFRARHTT
SCHEMBL15745652 0.81 AR (0.34) DHFRARPOLB
SCHEMBL4726719 0.80 HSPA5 (0.49) HSPA5DHFRARPOLBHTT
SCHEMBL15745658 0.79 ADRB2 (0.39) HSD11B1AR
SCHEMBL15745659 0.79 AR (0.30) AR
SCHEMBL15745661 0.79 ADRB2 (0.40) CFTRAR
SCHEMBL19465254 0.75 MEN1 (0.38) POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-20140148571-A1 Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed