Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | UBE2M | P61081 | 1/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | PPM1B | O75688 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574467 | 0.87 | RAB9A (0.52) | RAB9AFAAHGRIN2BALDH1A1HPGD | |
| SCHEMBL1575561 | 0.86 | RAB9A (0.50) | RAB9AFAAHGRIN2BALDH1A1HPGD | |
| SCHEMBL1575215 | 0.84 | GRIN2B (0.52) | RAB9AGRIN2BALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1574591 | 0.84 | RAB9A (0.48) | RAB9AFAAHGRIN2BALDH1A1HPGD | |
| SCHEMBL1574682 | 0.84 | ALDH1A1 (0.56) | RAB9AFAAHGRIN2BALDH1A1KMT2A | |
| SCHEMBL1574543 | 0.83 | GRIN2B (0.52) | RAB9AFAAHGRIN2BALDH1A1HPGD | |
| SCHEMBL1574581 | 0.83 | NPC1 (0.56) | FAAHALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL1575141 | 0.83 | GRIN2B (0.60) | RAB9AGRIN2BALDH1A1LMNAMEN1 | |
| SCHEMBL1574699 | 0.82 | RAB9A (0.49) | RAB9AALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL1574383 | 0.82 | L3MBTL1 (0.50) | RAB9AFAAHALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308562-B1 | Azetidine ring compounds and drugs comprising the same | ONO PHARMACEUTICAL CO (JP) | 2015-02-25 | — | — | EP | disclosed |
| EP-2308562-A2 | Azetidine ring compounds and drugs comprising the same | Ono Pharmaceutical Co., Ltd. (JP) | 2011-04-13 | — | — | EP | disclosed |
| US-7511159-B2 | Azetidine ring compounds and drugs comprising the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-03-31 | — | — | US | disclosed |
| US-20070135402-A1 | Azetidine ring compounds and drugs comprising the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | US | disclosed |
| EP-1698375-A1 | AZETIDINE RING COMPOUNDS AND DRUGS COMPRISING THE SAME | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135402-A1 | Azetidine ring compounds and drugs comprising the same | EDNRA, LIPG, EDNRB | RAB9A 898/4885FAAH 3484/4885GRIN2B 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.