Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12600789 | 0.88 | ADRA1A (0.50) | LMNAALDH1A1KDM4EHSD17B10ADRA1A | |
| SCHEMBL15746289 | 0.77 | ALDH1A1 (0.43) | LMNAALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL12565602 | 0.76 | ALDH1A1 (0.50) | LMNAALDH1A1KDM4EHSD17B10ADRA1A | |
| SCHEMBL3427457 | 0.76 | ALDH1A1 (0.50) | LMNAALDH1A1KDM4EHSD17B10ADRA1A | |
| SCHEMBL6251711 | 0.75 | ADRA1A (0.52) | ALDH1A1ADRA1AACHEGAAMAPT | |
| SCHEMBL9232769 | 0.75 | DRD2 (0.47) | LMNAALDH1A1KDM4EHSD17B10ADRA1A | |
| SCHEMBL17014320 | 0.73 | KDM4E (0.44) | LMNAALDH1A1KDM4EHSD17B10ADRA1A | |
| SCHEMBL18071530 | 0.72 | ALDH1A1 (0.46) | LMNAALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL24650805 | 0.72 | ADRA1A (0.68) | ALDH1A1KDM4EADRA1AACHEMAPT | |
| SCHEMBL18018511 | 0.72 | ADRA1A (0.52) | ALDH1A1KDM4EADRA1AACHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303061-B2 | Spiro compounds as Hepatitis C virus inhibitors | Sunshine Luke Pharma Co., Ltd. (CN) | 2016-04-05 | — | — | US | disclosed |
| US-20140147412-A1 | SPIRO COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140147412-A1 | SPIRO COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | HAVCR2, SORD, SLC10A1 | LMNA 1921/4885ALDH1A1 279/4885KDM4E 4827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.